DNA Damage, DNA Repair and Disease

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Product Information

ISBN9781788018890
PublisherRoyal Society of Chemistry
FormatHardcover
Number of pages428
Weight (kg)0.806
Publishing Date18/11/2020
Price (excl. tax)€253.68
Tax€15.22
Price (incl. tax)€268.90
Availability1 unit in external warehouse

Product Description

The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.