The Toxicant Induction of Irritant Asthma, Rhinitis, and Related Conditions

€ 172,90


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Informação do Produto

ISBN9781461490432
EditoraSpringer-Verlag New York Inc.
FormatoCapa dura
Número de páginas294
Peso (kg)0,568
Data de Publicação24/01/2014
Preço (iva excl.)€ 163,11
Imposto€ 9,79
Preço (iva inc.)€ 172,90
Disponibilidade1 unidade em armazém externo

Descrição do Produto

Untoward reactions to environmental chemicals, particularly when a subject reports difficulties with exposures to chemicals of diverse classes involving more than one organ system, have been poorly understood and an area of great controversy. Studies of airway inflammation induced by respiratory irritants have established neurogenic inflammation as the mechanism for irritant asthma and rhinitis. Remodeling of the airway after an acute irritant exposure can lead to a heightened sensitivity to irritants that persists. Recognition that rhinitis, while sometimes regarded as a trivial disease, is associated with extra-airway manifestations such as fatigue and disturbances of sleep, mood, and cognition, further elucidates how chemical exposures can be serious for susceptible individuals. This book reviews current scientific understanding of irritant airway inflammation and related conditions, including cardiovascular effects of particulate exposures, airborne contact dermatitis and irritant dermatitis, and the brain as a target organ for both allergic and irritant reactions. It is essential reading for physicians and other healthcare workers caring for patients with environmental intolerances. Allergists, toxicologists, occupational and environmental physicians, and pulmonologists will find the materials particularly valuable. Patients and advocates for those with chemical intolerances will also find the book of interest.