Epigenetic Alterations in Oncogenesis

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Informação do Produto

ISBN9781441999665
EditoraSpringer-Verlag New York Inc.
FormatoCapa dura
Número de páginas348
Peso (kg)0,666
Data de Publicação06/09/2012
Preço (iva excl.)€ 163,11
Imposto€ 9,79
Preço (iva inc.)€ 172,90
Disponibilidade1 unidade em armazém externo

Descrição do Produto

The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “above” genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book.